Activelle
Activelle is a hormone replacement therapy (HRT) medicine for women who have gone through menopause at least one year ago, used to relieve menopausal symptoms and prevent bone weakening (osteoporosis).
Form
tabletti, kalvopäällysteinen
Strength
1 mg / 0.5 mg
Active Ingredient
Estradiol hemihydrate
Manufacturer
Novo Nordisk A/S
How to Use
Dosage
Take one tablet once a day.
Method
Take the tablet at roughly the same time each day, with or without food.
Important
Do not take more than one tablet per day. If you miss a dose, do not take a double dose.
Possible Side Effects
COMMON
- •Breast pain or tenderness.
- •Vaginal bleeding.
- •Headache.
- •Weight gain due to fluid retention.
- •Vaginal inflammation or yeast infection.
- •New or worsening migraine.
- •Nausea.
- •Back pain.
- •Swelling of hands or feet.
- •Feeling depressed or worsening depression.
RARE
- •Bloating, stomach pain, or gas.
- •Acne or skin rash.
- •Hair loss or unusual hair growth.
- •Itching or hives.
- •Leg cramps.
- •Dizziness or restlessness.
- •Vomiting or heartburn.
- •Changes in sexual desire.
- •Gallbladder issues or gallstones.
- •Visual disturbances.
Important Warnings
- Do not take Activelle if you have or have had breast cancer or any cancer sensitive to estrogen.
- Stop taking Activelle and call your doctor right away if you notice signs of a blood clot (like painful swelling in your leg, sudden chest pain, or trouble breathing), a heart attack, or a stroke.
- Stop taking Activelle and seek immediate medical help if you get yellow skin/eyes, or severe allergic reactions like swelling of the face, tongue, or throat, or difficulty breathing.
- Activelle is not for use during pregnancy or breastfeeding, and it is not a birth control pill. If you are under 50 or it has been less than one year since your last period, you might need another form of contraception.
Use in Elderly Patients
Category D
Systemic use: Avoid use in older adults. In systemic use, consider potential adverse effects, such as risk of cardiovascular diseases and venous thromboembolism. Consider potential interactions. (updated 21.10.2024)